姓名：阳乐涛

导师情况：博士生导师

研究领域：生物材料

研究方向：

1. 靶向药物递送

2. 细胞生物力学

3. 神经组织工程

Email: yangletao@tongji.edu.cn

通讯地址：上海市杨浦区四平路1239号，同济大学生命科学与技术学院，邮编200092

个人简介

阳乐涛，博士，同济大学生命科学与技术学院教授，同济大学附属同济医院柔性引进人才，脊柱脊髓损伤再生修复教育部重点实验室PI。本科、博士和博士后分别就读于南开大学、美国罗格斯大学和哥伦比亚大学。课题组近年重点聚焦组织再生修复过程中的非可溶性微环境研究（包括力学微环境、胞间互作和细胞外基质微环境等），开发力学材料多组学技术、胞间互作调控元器件以及细胞靶向药物递送系统，挖掘再生修复靶点并提升干细胞治疗组织损伤的效果。在Nature Communications、Science Advances、Advanced Science、Advanced Materials、National Science Reviews、Research等期刊以通讯或第一（含共同）作者发表文章>20篇，总引用数3000余次，H-index为30。相关研究得到国家自然科学基金委、国家重点研发计划支持，获得Rutgers TechAdvance Award、Columbia TRx Award和国际神经再生修复学会青年论坛一等奖等奖项并入选国家高层次青年人才，受邀在World Biomaterials Congress、Tissue Engineering and Regenerative Medicine International Society -AP、China Nano等国际会议作报告，担任Exploration期刊（影响因子22.5，全球综合类期刊排名第五）副主编，兼任中国研究型医院学会神经再生与修复专委会常务委员。

代表性论文（*通讯作者，†共同第一作者）：

1.Yang L*, Jiang P, Stein J, Zhou C, Hou Y, Kang H*, Lee KB*. Mechanobiological Dynamics-Inspired Mechanomodulatory Biomaterials. Advanced Science, 2025. Accepted. 

2.Yang L, Rathnam, C., Hou, Y., Patel, M., Li, C., Lee, K.-B. Rapid and Programmable 3D Cell Sheet Assembly by Biodegradable Nanochannel Membrane, Advanced Functional Materials, 2025, 24(1): 2403367.

3.Yang L*, Bhujel B, Hou Y, Luo J, An SB, Han I*, Lee KB*. Effective Modulation of Inflammation and Oxidative Stress for Enhanced Regeneration of Intervertebral Discs Using 3D Porous Hybrid Protein Nanoscaffold. Advanced Materials. 2023, DOI: 10.1002/adma.202303021 

4.Yang L, Rathnam C, Hidaka T, Hou Y, Conklin B, Pandian GN, Sugiyama H, Lee KB. A Nanoparticle-based Artificial Mitochondrial DNA (mtDNA) Transcription Regulator: MitoScript. Nano Letters. 2023, 23, 5, 2046-2055.

5.Yang L, Conley B, Rathnam C, Cho HY, Lee JH, Lee KB. A Predictive Biophysical Cue Mapping Approach for Cellular Reprogramming Using Combinatorial Nanoarrays. ACS Nano. 2022, 16, 4, 5577–5586. 

6.Yang L, Conley B, Rathnam C, Pongkulapa T, Conklin B, Hou Y, Lee K.-B. High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine Learning Approach. Research. 2022, 9784273. 

7.Rathnam C.†, Yang L†, Castro-Pedrido S, Cai L, Lee K.-B. Hybrid SMART Spheroids for Enhanced Stem Cell-based Treatment of CNS Injuries. Science Advances. 2021, 7, 40. 

8.Yang L†, Conley B†, Cerqueira RS†, Pongkulapa T, Wang S, Lee JK, Lee KB. Effective Modulation of CNS Inhibitory Microenvironment using Bio-inspired Hybrid Nanoscaffold-based Therapeutic Interventions. Advanced Materials. 2020, 32, 2002578. 

9.Yang L, Kim TH, Cho HY, Chueng STD, Lee JM, Luo J, Yin PT, Han J, Kim JH, Chung BG, Choi JW, Lee, KB. Hybrid Graphene Oxide/Gold Nanoparticle-based Nucleic Acid Conjugates for Cancer-Specific Multimodal Imaging and Combined Therapeutics. Advanced Functional Materials. 2020, 31, 2006918. 

10.Yang L, Chueng STD, Li Y, Patel M, Rathnam C, Dey G, Wang L, Cai L, Lee KB. A Biodegradable Hybrid Inorganic Nanoscaffold for Advanced Stem Cell Therapy. Nature Communications. 2018, 9, 3147.