教授

阳乐涛

发布时间:2019-05-08  

姓名:阳乐涛


导师情况:博士生导师

研究领域:组织工程/生物材料


研究方向:

1. 促干细胞疗法的组织工程支架研发

2. 细胞命运的四维生物力学调控

3. 靶向蛋白/基因药递送

Email: yangletao@tongji.edu.cn

通讯地址:上海市杨浦区四平路1239号,同济大学生命科学与技术学院,邮编200092


个人简介

     阳乐涛,博士生导师,国家高层次青年人才计划获得者(2022)。2012年本科毕业于南开大学,2019年博士毕业于美国罗格斯大学,随后在罗格斯大学和哥伦比亚大学开展了博士后研究,20232月加入同济大学生命科学与技术学院。以多学科交叉和转化研究为特色,结合纳米技术和生物材料等前沿领域的最新进展,创新干细胞/基因疗法,用于治疗中枢神经系统等疾病。近五年在Nature CommunicationsScience AdvancesNational Science ReviewsResearchAdvanced MaterialsAdvanced Functional MaterialsACS NanoNano LettersBiomaterialsSmall等高水平期刊上以第一/共同第一作者发表文章13篇。共发表文章>40篇,总引用数~1700H-index为19。获得Rutgers TechAdvance AwardColumbia TRx Award等技术转化奖项。

 

近五年代表性论文(中科院1区,代表共同第一作者):  

1. Yang L*, Bhujel B, Hou Y, Luo J, An SB, Han I*, Lee KB*. Effective Modulation of Inflammation and Oxidative Stress for Enhanced Regeneration of Intervertebral Discs Using 3D Porous Hybrid Protein Nanoscaffold. Advanced Materials. 2023, DOI: 10.1002/adma.202303021 (*代表同济大学第一通讯作者单位)

2. Yang L, Rathnam C, Hidaka T, Hou Y, Conklin B, Pandian GN, Sugiyama H, Lee KB. A Nanoparticle-based Artificial Mitochondrial DNA (mtDNA) Transcription Regulator: MitoScript. Nano Letters. 2023, 23, 5, 2046-2055.

3. Yang L, Lin YH, Zhu Y, Ding S, Margolis KG, Leong KW. Material Engineering in Gut Microbiome and Human Health. Research. 2022, 9804014.

4. Yang L, Conley B, Rathnam C, Cho HY, Lee JH, Lee KB. A Predictive Biophysical Cue Mapping Approach for Cellular Reprogramming Using Combinatorial Nanoarrays. ACS Nano. 2022, 16, 4, 5577–5586.

5. Yang L, Patel KD, Rathnam C, Thangam R, Hou Y, Kang H, Lee KB. Harnessing the Therapeutic Potential of Extracellular Vesicles for Biomedical Applications Using Multifunctional Magnetic NanomaterialsSmall. 2022, 18, 2104783.

6. Yang L, Conley B, Rathnam C, Pongkulapa T, Conklin B, Hou Y, Lee K.-B. High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine Learning ApproachResearch. 2022, 9784273.

7.Yang L†, Conley B†, Cerqueira RS†, Pongkulapa T, Wang S, Lee JK, Lee KB. Effective Modulation of CNS Inhibitory Microenvironment using Bio-inspired Hybrid Nanoscaffold-based Therapeutic Interventions. Advanced Materials. 2020, 32, 2002578. 

8. Yang L, Kim TH, Cho HY, Chueng STD, Lee JM, Luo J, Yin PT, Han J, Kim JH, Chung BG, Choi JW, Lee, KB. Hybrid Graphene Oxide/Gold Nanoparticle-based Nucleic Acid Conjugates for Cancer-Specific Multimodal Imaging and Combined TherapeuticsAdvanced Functional Materials202031, 2006918. 

9. Yang L, Lee J.-H., Rathnam C, Hou Y.-N, Choi J.-W, Lee K.-B. Dual-Enhanced Raman Scattering-based Characterization of Stem Cell Differentiation using Graphene-Plasmonic Hybrid NanoarrayNano Letters. 2019, 11, 8138-8148.

10. Yang L, Chueng STD, Li Y, Patel M, Rathnam C, Dey G, Wang L, Cai L, Lee KB. A Biodegradable Hybrid Inorganic Nanoscaffold for Advanced Stem Cell Therapy. Nature Communications. 2018, 9, 3147.

11.Conley BM†, Yang L†, Basanta B, Luo J, Han I, Lee KB. Development of a Nano-Hybrid Peptide Hydrogel for Enhanced Intervertebral Disc Repair and Regeneration. ACS Nano. 2023, 17, 4, 3750-3764. († means equal contributions) 

12.Wang S†, Yang L.† et al. Injectable Hybrid Inorganic Nanoscaffold-templated Rapid Stem Cell Assembly for Accelerated Cartilage Repair. National Science Review. 2022, 9, nwac037. († means equal contributions)

13. Rathnam C., Yang L, Castro-Pedrido S, Cai L, Lee K.-B. Hybrid SMART Spheroids for Enhanced Stem Cell-based Treatment of CNS Injuries. Science Advances. 2021, 7, 40.

14. Wang S.-Q., Yang L, Cho H.-Y, Chueng S.-T.-D, Zhang H.-P, Zhang Q.-Y, Lee K.-B. Developing Redox and Light Responsive Core-shell Nanoparticle for Photo-Chemical Enhanced Chemodynamic Therapy. Biomaterials. 2019, 224, 119498.

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