姓名：静国欣

学位：博士

导师情况：硕士生导师

研究领域：纳米生物医学

E-mail：jingguoxin@tongji.edu.cn

通讯地址：上海市杨浦区四平路1239号医学楼1119

研究方向：

（1）纳米材料调控干细胞命运的功能及机制研究

（2）免疫调控型纳米载药体系的构建

个人简介：

静国欣，博士，助理教授，硕士生导师。本科毕业于辽宁大学生命科学院，研究生就读于同济大学生命科学与技术学院（导师：汪世龙教授），2020年获生物学博士学位。2020-2023年于同济大学生物医学工程流动站从事博士后工作。2023年受聘于同济大学生命科学与技术学院任助理教授。

静国欣博士研究方向为干细胞及免疫细胞命运调控型生物活性材料的设计与构建。研究成果发表于Biomaterials, Advanced Composites and Hybrid Materials, Chemical Engineering Journal等国际知名学术期刊上，获授权专利3项。主持国家自然科学基金青年项目（2025）、上海市科委“启明星培育”项目（2024）、博士后科学基金面上项目（2021）、上海市“超级博士后”激励计划（2020）。曾获同济大学优秀出站博士后（2023）、同济大学优秀博士论文（2020）、博士研究生国家奖学金等荣誉奖励。 

代表论文：

（1）Chaoran Wu, Hong Wang, Jintong Niu, Bangguo Wei, Yi Gao, Youyuan Li, Huichao Wang, Qingyun Lyu, Guoxin Jing*, Hongbao Wang*, Shilong Wang*, Combination of an LDH-based platform with microRNA for the treatment of myocardial Ischemia-Reperfusion injury by pyroptosis inhibition via the CaSR/PLCγ1/IP₃R pathway, Chemical Engineering Journal, 2025, 508,160833.

（2）Guoxin Jing^#, Youyuan Li^#, Feiyue Sun, Qiang Liu, Ai Du, Hong Wang, Jintong Niu, Jialu Lu, Yechang Qian*, Shilong Wang*, Near-infrared light-activatable upconversion nanoparticle/curcumin hybrid nanodrug: a potent strategy to induce the differentiation and elimination of glioma stem cells. Advanced Composites and Hybrid Materials, 2024, 7(3),82.

（3）Guoxin Jing, Linnan Yang, Hong Wang, Jintong Niu, Huichao Wang, Yi Gao, Youyuan Li, Bangguo Wei, Yechang Qian^*, Shilong Wang^*, Blocked Autophagy is Involved in Layered Double Hydroxide-Induced Repolarization and Immune Activation in Tumor-Associated Macrophages. Advanced Healthcare Materials, 2023, 2301471

（4）Lili Qin^#, Guoxin Jing^#, Ningxin Cui, Zhen Xu, Yiwei He, Yao Qin, Tianfeng Lu, Jingyu Sun, Ai Du^*, Shilong Wang^*, Resveratrol-Silica Aerogel Nanodrug Complex System Enhances the Treatment of Sports Osteoarthritis by Activating SIRT-1. Advanced Composites and Hybrid Materials, 2023, 6(3).

（5）Guoxin Jing^#, Linnan Yang^#, Hong Wang, Jintong Niu, Youyuan Li, Shilong Wang^*. Interference of layered double hydroxide nanoparticles with pathways for biomedical applications. Advanced Drug Delivery Reviews, 2022, 188:114451.

（6）Guoxin Jing, Kun Li, Feiyue Sun, Jintong Niu, Rongrong Zhu, Yechang Qian^*, Shilong Wang^*.Layer-number-dependent effects of graphene oxide on the pluripotency of mouse embryonic stem cells through the regulation of the interation between the extracellular matrix and integrins.International Journal of Nanomedicine, 2021, 16:3819-3832.

（7）Guoxin Jing, Zhaojie Wang, Xizhen Zhuang, Xiaolie He, Huijun Wu, Qingxiu Wang, Liming Cheng, Zhongmin Liu, Shilong Wang^*, Rongrong Zhu^*. Suspended graphene oxide nanosheets maintain the self-renewal of mouse embryonic stem cells via down-regulating the expression of Vinculin. Biomaterials, 2018, 171:1-11.

授权专利：

（1）汪世龙，王虹，静国欣，牛金童，李有元，一种层状双氢氧化物-酞菁锌纳米复合体的方法及应用，中国ZL202210901177.3

（2）汪世龙，牛金童，静国欣，王虹，李有元，纳米层状双氢氧化物在炎性肠病中的应用,

中国，ZL20221089 9368.0

（3）汪世龙，朱融融，静国欣，纳米氧化石墨烯在促进小鼠胚胎干细胞培养和自我更新中的应用，中国，ZL201610817382.6