报 告 人： Wenxian Fu, Ph.D. Assistant Professor， Department of Pediatrics University of California, San Diego, USA
主 持 人： 张勇 教授
时        间： 2017年6月29日周四上午10:00
地        点： 医学大楼1102会议室

Abstract
Inflammation is an evolutionally-selected protective mechanism. However, uncontrolled inflammation has deleterious consequences, characterized by tissue damage and disease onset. However, the genesis and regulation of each of disease-associated inflammation remain elusive. Macrophages, a special subset of immune cells, play a key role in orchestrating the initiation, progression and resolution of inflammation. However, tissue macrophages are highly heterogeneous and functionally plastic. The identification of new types of macrophages in pancreatic islets and their roles in controlling autoimmunity, metabolic process and beta cell function will be discussed.  The goal is to develop new therapeutics for diabetes by modulating and harnessing macrophages.
简介
付文先博士，本科和博士毕业于北京大学，在美国哈佛大学完成博士后研究。现任美国加州大学圣地亚哥分校（UCSD）医学院助理教授。专注于研究免疫系统对复杂疾病（包括糖尿病和癌症等）发病机理的影响。主要研究兴趣是寻找和鉴定新型免疫细胞和分子对组织炎症的调控以及相关机理。已经在Nature Immunology, Science Translational Medicine, Diabetes等杂志发表文章多篇。曾获American Diabetes Association Fellowship, Harvard Medical School Schuyler Pierce Memorial Fellowship,  UCSD Dean’s Research Award, JDRF Strategic Research Award 等。