主    题：Programming and Reprogramming: What Does It Take to Make a Cardiomyocyte?
报告人：钱莉，Dr. Li Qian
主持人：项耀祖
时   间：2016年8月9日 周二 10:00-11:30
地   点：医学楼1102

Biography

      Dr. Li Qian graduated from Fudan University, China, and obtained her PhD degree at University of Michigan, Ann Arbor, in 2006. Now She is tenure-track Assistant Professor in University of North Carolina at Chapel Hill. Her research is currently focusing on developing innovative approaches to regenerate or repair an injured heart. In the last 5 years, Dr. Qian has published 30 articles, such as Nature, Nature Protocols, JEM, Developmental Cell, JCB, etc. Dr. Qian was awarded several important prizes including ‘Katz Prize in Basic Science Research’ (AHA) and ‘Boyalife, Science and STM Award in stem cells and Regenerative Medicine’（Sciecne/AAAS）.

Employment and Education

2012-now, Assistant Professor, University of North Carolina at Chapel Hill, USA
2007-2012, Postdoc Fellow, Gladstone Institute for Cardiovascular Research, UCSF, USA.
2001-2006, PhD, University of Michigan, Ann Arbor, USA.

Selected Publications

1.Qian L. (2016) Hope for the brokenhearted: cellular reprogramming improves cardiac function in a mouse model of myocardial infarction. Science 352 (6292), 1400-1401
2.Qian L., Huang Y, Foley A, Vedantham V, Spencer CI, Conway SJ, Fu JD, Srivastava D. (2012) In vivo reprogramming of murine cardiac fibroblasts into cardiomyocytes. Nature. 485, 593–598
3.Qian L., Berry E.C., Fu J.D., Ieda M., and Srivastava D. (2013) Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro. Nature Protocols. 8, 1204-15
4.Wang L., Liu Z., Yin C., Asfour H., Chen O., Li Y., Bursac N., Liu J. and Qian L*. (2015) Stoichiometry of Gata4, Mef2c and Tbx5 influences the efficiency and quality of iCM reprogramming. Circ Res. 116, 237-244
5.Qian L. and Srivastava D. (2013) Direct Cardiac Reprogramming: From Developmental Biology to Cardiac Regeneration. Circ. Res. 113, 915-21