报告人： Xiangjian Zheng, Ph.D.
Lab of Cardiovascular Signaling
Centenary Institute, University of Sydney
Sydney, Australia

主持人： 高绍荣教授

时间： 2016年5月27日周五上午10:00

地点： 医学大楼1102会议室

PROFESSIONAL EXPERIENCE

Lab Head and Associate Faculty 2014-
Lab of Cardiovascular Signaling, Centenary Institute, University of Sydney, Australia

Conjoint Senior Lecturer 2014-
Sydney Medical School, University of Sydney, Sydney, Australia
Major research areas: Cardiovascular Diseases and Development, Endothelium in organ development and regeneration
 

Research Associate 2011-2014
Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
Major research areas: CCM signaling pathway, Cardiovascular Development, Tumor Angiogenesis, Mouse Genetics, Zebrafish Model

Postdoctoral Fellow 2006-2011
Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
Mentor: Mark L. Kahn
Major research areas: CCM signaling pathway, Cardiovascular Development, Mouse Genetics, Zebrafish Model

PUBLICATIONS

1. Zhou Z, Tang AT, Wong W, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur SC, Whitehead KJ, Awad IA, Li DY, Zheng X, and Kahn ML. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signaling. Nature 532: 122-126 (2016)
2. Zhou Z, Rawnsley D, Goddard L, Pan W, Cao X, Jakus Z, Zheng H, Yang J, Arthur S, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X* and Kahn ML*. The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression. Dev Cell 32(2): 168-180 (2015) (* co-corresponding author).
3. Zheng X, Riant F, Bergametti F, Myers CD, Tang AT, Kleaveland B, Pan W, Yang J, Tounier-Reserve E and Kahn ML. Cerebral cavernous malformations arise independent of heart-of-glass receptor. Stroke 45(5): 1505-09 (2014).