Education & Training：
Maoquan Chu received his Ph.D. degree from East China University of Science and Technology in 2001. He then did his postdoctoral work in School of Life Science and Technology in Shanghai Jiaotong University, where he delved into nano-biomedicine. In 2004, he joined the School of Life Science and Technology in Tongji University.
Research Interests：
Our major research focus are:
1) Advanced nanostructures for in vivo target drug delivery
2) Advanced nanostructures and strategy for in vivo cancer target imaging and therapy
Research Description：
To date cancer is considered as one of the world's most devastating diseases bringing the total death toll to approximately 7000000 per year. The current challenges in effective cancer treatment lie on finding novel approaches for early cancer diagnosis and targeted therapy. Nanobiotechnology has great potential to revolutionize cancer accurate diagnosis and treatment. In recent years, our group has developed semiconductor quantum dots (including self-illuminating quantum dots) for molecular imaging, highly sensitive in vivo real-time luminescent mapping of sentinel lymph nodes, as well as cancer photothermal and photodynamic therapy. We also developed graphene quantum dots, graphene oxide nanosheets, gold nanoparticles, magnetic nanoparticles, polymer nanospheres and micells, DNA and liposomes for in vivo target drug delivery and multimodal cancer therapy. In these nanobiomedicine researches, we investigated the cancer specific markers, the apoptosis mechanism of tumor and biophysicochemical interactions at the nano–bio interface, as well as nanotoxicology. Our ultimate goal is to develop advanced nanocarriers and novel strategy for relatively non-invasive, early, and accurate cancer diagnosis and high efficient target therapy.
Key Word: Nanobiomedicine, cancer, target drug delivery, molecular imaging, multimodal therapy
