Name : Lei Xue
Address : School of Life Science Tongji University 1239 Siping Road Shanghai, China
E-mail :    lei.xue@tongji.edu.cn
Education:
1983 -1987      Bachelor of Science, Department of Biology, Beijing University, China
1987 -1990      Master of Science, Institute of Cell Biology, Chinese Academy of Science
1993 -1998      Ph. D, Institute of Molecular Biology, University of Zürich, Switzerland
 

Teaching & Research Experience:
1998 - 2000      Postdoctoral Research Associate, University of Zürich, Switzerland
2000 - 2001      Postdoctoral Associate, Yale University, USA
2001 - 2006      Research Associate, Howard Hughes Medical Institute, USA
2006 - 2008      Research Specialist, Howard Hughes Medical Institute, USA
2008 –                  Professor, School of Life science, Tongji University, China

Selected Publications :

1. X Wang, Z Wang, Y Chen, X Huang, Y Hu, R Zhang, M S Ho and L Xue* (2014）FoxO Mediates APP-Induced AICD-Dependent Cell Death. Cell Death Dis. 5, e1233; doi:10.1038/cddis.2014.196
2. Y Hu, Y Han, X Wang and L Xue* (2014) Aging-related Neurodegeneration Eliminates Male Courtship Choice in Drosophila. Neurobiology of Aging 35, 2174-2178
3. X Ma, W Li, H Yu, Y Yang, M Li, L Xue* and T Xu* (2014) Bendless modulates JNK-mediated cell death and migration in Drosophila. Cell Death Diff. 21, 407-415.
4. Y Wang and L Xue* (2014) Mapping It out: A Novel Signaling Pathway Linking Aβ-PrPc-Fyn Complex to Cognitive Impairment in Alzheimer’s Disease. Adv. Alz. Dis. 3, 20-23.
5. X Ma, Y Shao, H Zheng, M Li, W. Li and L. Xue* (2013) Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila. Cell Death Dis. 4, e864.
6. H. Yang, W. Li, H. Yu, R. Yuan, Y. Yang, K. Pung, P. Li and L. Xue* (2013) Physiological Effects of L-Theanine on Drosophila melanogaster. Molecules 18,13175-13187
7. X. Ma, L. Yang, Y. Yang, M. Li, W. Li* and L. Xue* (2013) dUev1a Modulates TNF-JNK Mediated Tumor Progression and Cell Death in Drosophila. Dev. Biol. 380, 211-221.
8. L. Pung, X. Wang, M. Li, L. Xue* (2013) The role of APP in Alzheimer’s disease. Adv. Alz. Dis. 2, 60-65
9. X. Ma, J. Huang, Y. Yang, W. Li and L. Xue* (2012) NOPO Modulates Egr- induced JNK- independent cell death in Drosophila. Cell Res. 22,425-431.
10. W. Li, S. Li, S. Zhang and L. Xue* (2012) A Broad Expression Profile of the GMR-GAL4 driver in Drosophila melanogaster. Genet. Mol. Res.11, 1997-2002.
11. J. Liu*, M. Ghanim*, L. Xue* et al., (2009) Analysis of Drosophila Segmentation Network Identifies a JNK Pathway Factor Overexpressed in Kidney Cancer. Science 323:1218-1222. (* Equal contribution)
12. L. Xue, T. Igaki, E. Kuranaga, H. Kanda, M. Miura and T. Xu (2007) Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila. Dev. Cell 13:446-454.
13. L. Xue and M. Noll. (2002) Dual role of the Pax gene paired in accessory gland development of Drosophila. Development 129:339-46.
14. L. Xue, X. Li and M. Noll. (2001) Multiple protein functions of paired in Drosophila development and their conservation in the Gooseberry and Pax3 homologs. Development 128:395-405.
15. L. Xue and M. Noll. (2000) Drosophila female sexual behavior induced by sterile males showing copulation complementation. Proc. Natl. Acad. Sci. USA 97: 3272-3275.         
16. L. Xue and M. Noll. (1996) The functional conservation of proteins in evolutionary alleles and the dominant role of enhancers in evolution. EMBO. J., 15: 3722-3731.