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张晓艳
来源:  作者:  发表时间:2011-11-10  阅读次数:15176次

 

姓        名: 张晓艳

 学       位:博士

导师情况:博士生导师

研究领域: 生物信息学

研究方向: 生物医学信息学

E-mailxyzhang@tongji.edu.cn

联系电话:021-65980233

通讯地址: 上海市四平路1239号,同济大学生命科学与技术学院(200092)

个人简介

2006 -现在:同济大学生命科学与技术学院

2000-2003:复旦大学生命科学学院植物学专业博士生,2003年6月获理学博士学位

1998-1999:美国密执安州立大学林学系博士生

1995-1997:美国新墨西哥州高地大学生命科学学院硕士生,1997年12月获科学硕士学位

1984-2000:中国科学院武汉植物研究所

 

主要科研项目:

2012-2014:人乳头瘤病毒HPV与内源性miRNA相互作用模型的建立及其致癌危险性研究,自然科学基金(合作申请)
2012-2014:建立疾病相关基因突变信息分析平台,上海市卫生局科研项目,主持
2012-2015:病毒整合位点模式特征识别,上海市自然科学基金,主持。
2008—2011:利用小鼠基因剔除技术发现新的基因工程药物,863计划 副组长
2007-2010:建立基于临床医疗信息共享平台的医疗决策支持系统,863计划 主要参加者
2003-2007:基因功能预测的系统发育分析模型与检验方法, 973项目 主要参加者

 

近年发表文章情况:

1.Yang, X., Li, M., Liu, Q., Zhang, Y., Qian, J., Wan, X., Wang, A., Zhang, H., Zhu, C., Lu, X., Mao, Y., Sang, X., Zhao, H.*, Zhao, Y.* and Zhang, X.* 2015, Dr. VIS v2.0: an updated database of human disease-related viral integration sites in the era of high-throughput deep sequencing. Nucleic Acids Res. 43, D887–D892. 
2.Yuan, W., Huang, T., Yu, J., Zeng, L., Lian, B., He, Q., Li, Y., Zhang, X.*, Zhou, F.*, and Xie, L*. 2014, Comparative analysis of viral protein interaction networks in Hepatitis B virus and Hepatitis C virus infected HCC. Biochim. Biophys. Acta 1844, 271–279.
3.Xiaoping Xiao, Yang Liu, Xiaoyan Zhang, Jing Wang, Zuofeng Li, Xiaojing Pang, Penghua Wang, Gong Cheng, 2014, Complement-Related Proteins Control the Flavivirus Infection of Aedes aegypti by Inducing Antimicrobial Peptides, PLOS Pathogens, , Volume 10 ( 4) e1004027
4. Xin Zhao, Qi Liu, Qingqing Cai, Yanyun Li, Congjian Xu, Yixue Li, Zuofeng Li,*and Xiaoyan Zhang1,* Dr.VIS: a database of human disease-related viral integration sites, Nucl. Acids Res. (2011) Nucleic Acids Research, 2012, Vol. 40, Database issue D1041–D1046(SCI 通讯作者)
5. Zuofeng Li, Xingnan Liu, Jingran Wen,Y, e Xu, Xin Zhao, Xuan Li, Lei Liu*, and Xiaoyan Zhang,* DRUMS: A human disease related unique gene mutation search engine, 2011, HUMAN MUTATION Database in Brief 32: E2259-E2265 (2011) Online (SCI 通讯作者)
6. Yang Yang, Zuofeng Li, Peng Nan, Xiaoyan Zhang*,2011,Drug-induced glucose-6-phosphate dehydrogenase deficiency-related hemolysis risk assessment, Computational Biology and Chemistry 35 (2011) 189–192 (SCI 通讯作者)
7. Wei W.Q., Liu F.Q., Liu L., Li Z.F., Zhang X.Y., Jiang F., Shi Q., Zhou X.Y., Sheng W.Q., Cai S.J., Li X., Xu Y., Nan P. Distinct mutations in MLH1 and MSH2 genes in Hereditary Non-polyposis Colorectal Cancer (HNPCC) families from China. BMB Rep, 2011 May;44(5):317-22. (SCI )
8. Liu Xinyi, Li Zuofeng,Cai Qingqing,Zhang Xiaoyan*. Prediction of multiple drug resistance phenotype in cancer cell lines using gene expression profiles and phylogenetic trees. Chinese Sci Bull, 2010, 55: 3778−3786 (SCI 通讯作者)
9. Xin Zhao, Zoufeng Li, Xiaoyan Zhang*. 2010. G6PD-MutDB: A MUTATION AND PHENOTYPE DATABASE OF GLUCOSE-6-PHOSPHATE (G6PD) DEFICIENCY. Journal of Bioinformatics and Computational Biology. Volume: 8, Supplementary Issue 1(2010) pp. 101-1099
10. Qingqing Cai, Zoufeng Li, Xiaoyan Zhang*. MiRNAs as promising phylogenetic markers for inferring deep metazoan phylogeny and in support of Olfactores hypothesis. BIBM'2010. pp.101~104
11. Qiang Zeng, Xiaoyan Zhang*…., Extracting Clinical Information from Free-text of Pathology and Operation Notes via Chinese Natural Language Processing, 2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops
12. Liu Xinnan, Xu Ye, Li Zuofeng, Liu Lei and Zhang Xiaoyan*,2009,ESCPP: An Evaluation and Alerting System for the Compatibility between Practice Guidelines and Practicing Medicine Using Arden Syntax
13. Wen Jingran, Zhang XIaoyan*, Xu Ye, Li Zuofeng and Liulei, Comparation of AdaBoost and Logistic Regression for Detection Colorectal Cancer Patients with Synchronous Liver Metastasis(ICBPE2009)(EI Accession number:20101612851195)
14. Gong Cheng,1,* Xin Zhao,1,* Zuofeng Li, Xinyi Liu, Weiyao Yan, Xiaoyan Zhang, Yang Zhong, and Zhaoxin Zheng1Identification of a Putative Invertebrate Helical Cytokine Similar to the Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor Family by PSI-BLAST-Based Approach,2009 Journal of Interferon & Cytokine Research,Vol 29(8) 462-468 (SCI )
15. HAO Pei,YU Yao, ZHANG Xiaoyan, …etc. The contribution of cis-regulatory elements to head-to-head gene pairs’ co-expression pattern, Sci China Ser C-Life Sci Jan.2009,52(1)74-79 (SCI )

 

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