李平

  

姓名:李平
学位:博士
导师情况:博士生导师/硕士生导师
研究领域:生物技术
E-mail:liping01@tongji.edu.cn
通讯地址:上海市杨浦区四平路1239号同济大学生命科学与技术学院(200092)
个人简介:
博士,现任同济大学生命科学与技术学院教授,博士生/硕士生导师。多年从事微生物发酵及酶学领域的科研与教学工作。先后主持与参加国家自然科学基金,农业部转基因重大专项,上海市科委项目,国家973前期研究专项、863项目、科技支撑项目等多项课题,参编教材2部。曾获省级优秀青年科技创新奖及省级科学技术三等奖。

研究方向:
1)微生物与酶工程:生物酶(茶氨酸合成同工酶、β-葡萄糖苷酶等)的微生物筛选、基因克隆、异源表达、结构解析、定向进化与合成调控。以及磁性纳米颗粒、纳米纤维等技术固定化酶和细胞。
2)食品营养、安全与健康:茶与食品中活性组分(茶氨酸、茶多酚及microRNA等)的功效、生物合成及作用机制。
代表性论文:
1.Yu Siran, Zhao Zhehao, Xu Xiaoyan, Li Min, Li Ping*. Characterization of three different types of extracellular vesicles and their impact on bacterial growth. Food Chemistry. 2019. 271. 372–378.
2.Nie Tao, Huang Antian, Li Ping*. Epigallocatechin gallate-mediated cell death is triggered by accumulation of reactive oxygen species induced via the cpx two-component system in escherichia coli. Frontiers in Microbiology. 2018. 9(246).
3.Zhao Zhehao, Yu Siran, Li Min, Gui Xin, Li Ping*. Isolation of Exosome-Like Nanoparticles and Analysis of MicroRNAs Derived from Coconut Water Based on Small RNA High-Throughput Sequencing. Journal of Agricultural and Food Chemistry. 2018. 66(11). 2749-2757.
4.Xi Jiajie, Wu Yukang, Li Guoping, Ma Li, Feng Ke, Guo Xudong, Jia Wenwen, Wang Guiying, Yang Guang, Li Ping*, Kang Jiuhong*. Mir-29b Mediates the Neural Tube versus Neural Crest Fate Decision during Embryonic Stem Cell Neural Differentiation. Stem Cell Reports. 2017. 9(2). 571-586.
5.Ye Yuemei, Xiao Linlin, He Bin*, Zhang Qi, Nie Tao, Yang Xinrui, Wu Dongbei, Cheng Heli, Li Ping*, Wang Qigang*. Oxygen-tuned nanozyme polymerization for the preparation of hydrogels with printable and antibacterial properties. Journal of Materials Chemistry B. 2017. 5(7). 1518-1524.
6.Feng Junchen, Yu Siran, Mo Ting, Li Ping*. Enhancement of the catalytic activity and stability of immobilized aminoacylase using modified magnetic Fe3O4 nanoparticles. Chemical Engineering Journal. 2016. 286. 216-222.
7.Li Haizhou, Yang Qunhui, Gao Hang, Li Ping*, Zhou Huaiyang*. The impact of temperature on microbial diversity and AOA activity in the Tengchong Geothermal Field, China. Scientific Reports. 2015. 5(17056). 17056.
8.Su Yajuan, Wang Yan, Li Ping*. Antibacterial property and mechanism of a novel Pu-erh tea nanofibrous membrane. Applied Microbiology and Biotechnology. 2012. 93(4). 1663–1671.
9.Wang Yan, Zhang Qun, Li Ping*. Composite electrospun nanomembranes of fish scale collagen peptides/chito-oligosaccharides: antibacterial properties and potential for wound dressing. International Journal of Nanomedicine. 2011. 6. 667-676.
10.Li Ping*, Su Yajuan, Wang Yan, Liu Bo, Sun Liming. Bioadsorption of methyl violet from aqueous solution onto Pu-erh tea powder. Journal of Hazardous Materials. 2010. 179(1-3). 43-48.
11.Yongxing He, Long Gui, Yinzi Liu, Yang Du, Yeyun Zhou, Ping Li*, Congzhao Zhou*.  Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly. Proteins. 2009. 76(1):249-254
12.Li Ping, Wan Xiaochun*, Zhang Zhengzhu, Shen Zuojun. A novel assay method for theanine synthetase activity by capillary electrophoresis. Journal Chromatography B.  2005. 819(1). 81–84.
13.Li Ping, Li Juan, Wu Changzhu, Wu Qingsheng*.  Synergistic antibacterial effects of β-lactam antibiotic combined with silver nanoparticles. Nanotechnology.  2005. 16(9). 1912-1917.

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